The B1 Deficiency That Can Shut Down Your Gut

Severe thiamine deficiency can affect far more than nerves and the heart. This clip explains GI beriberi, a lesser-known form of B1 deficiency associated with lactic acidosis, nausea, vomiting, severe constipation, and in extreme cases, near-total loss of stomach and intestinal movement.

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What If Parkinson’s Is Also An Energy Metabolism Problem?

Parkinson’s is often framed around dopamine, but this clip looks deeper at what may be happening inside the cell. Oxidative stress, inflammation, chronic infection, and environmental toxins can interfere with key thiamine-dependent enzymes involved in energy production, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. That raises a bigger question about whether impaired B1-dependent metabolism is part of the disease process itself.