DS Haven In Light Of Things
High-dose thiamine can sometimes help dramatically at first, then start producing completely different symptoms later. This clip explains why people correcting a B1 deficiency may eventually need to reduce the dose, especially if signs of sympathetic nervous system overdrive begin appearing after months of improvement.
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What If Parkinson’s Is Also An Energy Metabolism Problem?
Parkinson’s is often framed around dopamine, but this clip looks deeper at what may be happening inside the cell. Oxidative stress, inflammation, chronic infection, and environmental toxins can interfere with key thiamine-dependent enzymes involved in energy production, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. That raises a bigger question about whether impaired B1-dependent metabolism is part of the disease process itself.