DS Haven In Light Of Things
This clip breaks down one of the earliest ways low thiamine may start showing up: the communication between the brain and the gut begins to break down. That matters because this whole pathway runs through the vagus nerve and depends heavily on acetylcholine. If B1 is too low, the signal can get weaker, the timing can get thrown off, and the gut starts losing clear instructions. What looks like a digestion problem may actually start much higher up the chain.
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What If Parkinson’s Is Also An Energy Metabolism Problem?
Parkinson’s is often framed around dopamine, but this clip looks deeper at what may be happening inside the cell. Oxidative stress, inflammation, chronic infection, and environmental toxins can interfere with key thiamine-dependent enzymes involved in energy production, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. That raises a bigger question about whether impaired B1-dependent metabolism is part of the disease process itself.