Why You May Absorb Only A Fraction Of The B1 You Take

Taking 200 mg of thiamine doesn’t necessarily mean your body gets 200 mg. Standard forms like thiamine hydrochloride rely on transport proteins in the gut, cells, and brain that can become saturated. This clip explains why that creates a bottleneck in B1 absorption and why increasing the dose doesn’t always translate into the same increase in thiamine reaching your tissues.

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What If Parkinson’s Is Also An Energy Metabolism Problem?

Parkinson’s is often framed around dopamine, but this clip looks deeper at what may be happening inside the cell. Oxidative stress, inflammation, chronic infection, and environmental toxins can interfere with key thiamine-dependent enzymes involved in energy production, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. That raises a bigger question about whether impaired B1-dependent metabolism is part of the disease process itself.