DS Haven In Light Of Things
Your body doesn’t keep expensive metabolic machinery running when it isn’t being used. This clip explains how enzymes involved in energy production can become downregulated during nutrient deficiency or changes in fuel use, and why high-dose nutrient therapy is being explored as a way to help reactivate those pathways. In chronic illness, the issue may not always be a lack of fuel. Sometimes the machinery needed to use that fuel is no longer working efficiently.
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What If Parkinson’s Is Also An Energy Metabolism Problem?
Parkinson’s is often framed around dopamine, but this clip looks deeper at what may be happening inside the cell. Oxidative stress, inflammation, chronic infection, and environmental toxins can interfere with key thiamine-dependent enzymes involved in energy production, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. That raises a bigger question about whether impaired B1-dependent metabolism is part of the disease process itself.